PP8 THE RELATIONSHIP OF BLOOD EOSINOPHIL LEVELS WITH THE LEVEL OF EXACERBATION, SHORTNESS OF BREATH LEVELS, AND HOSPITALIZATION EVENT IN ASTHMA PATIENTS AT THE UNIVERSITY OF NORTH SUMATERA (USU) HOSPITAL’S PULMONARY POLYCLINIC

Rizki Amaliyah Damanik1, Andika Pradana2, Pandiaman Pandia 2
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia1
Division of Asthma and COPD, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara2

Introduction:

Asthma is a heterogeneous disease with chronic airway inflammation characterized by symptoms like wheezing, shortness of breath, and coughing. Eosinophil infiltration distinguishes it from other airway inflammatory disorders, primarily triggered by allergen inhalation.

Objectives:

To understand the relationship between blood eosinophil levels with exacerbation levels, shortness of breath levels, and hospitalization events in Asthma patients at the USU Hospital’s pulmonary polyclinic.

Methdos:

A retrospective cohort study at USU Hospital examined the relationship between blood eosinophil levels and exacerbation levels, shortness of breath levels, and hospitalization events in outpatients with asthma from June-October 2023 using The Mann-Whitney test.

Results:

Total of 25 samples, the majority of whom were women as many as 20 people (80%), with an eosinophil level <100 as many as 21 people (84%), patients who had never been hospitalized as many as 18 people (72%), the level of severe exacerbations was 18 people (72%), the degree of uncontrolled asthma was 10 people (40%) and the age range was 26-50 years as many as 11 patients (44%). The results of this research obtained a p value of 0.976, because the p value was greater than 0.05, there was no correlation between eosinophil levels and exacerbation levels, shortness of breath levels, or hospitalizations among asthma patients at the USU Hospital pulmonary polyclinic.

Conclusions:

The rate of exacerbations, shortness of breath levels, and hospitalization that occur in asthma are not always caused by increased eosinophil levels. Several other factors can influence them.