PP5 RELATIONSHIP BETWEEN MICROBIAL PATTERNS AND RESISTANCE TESTING WITH MORTALITY IN PNEUMONIA PATIENTS AT THE ICU OF H. ADAM MALIK GENERAL HOSPITAL

Agnes Nadia1, Syamsul Bihar2, Fajrinur Syarani2, Noni N. Soeroso3
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia1
Division of Pulmonary Intervention, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara2
Division of Pulmonary Oncology, Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Sumatera Utara3

Introduction:

The Intensive Care Unit’s (ICU) patients account for 20–50% of all mortality, and the risk is increased by nosocomial infections. Bronchoalveolar Lavage (BAL) examinations are crucial for precisely treating antibiotics, identifying lower respiratory tract infections, and lowering hospital mortality.

Objectives:

To understand whether microbial patterns and resistance testing relate to mortality in Pneumonia cases in the ICU, as determined by BAL examinations. 

Methods:

A quantitative method with a cross-sectional study design and chi square test to examine the relationship between microbial patterns and resistance testing with mortality. Pneumonia patients diagnosed radiologically, aged over 18 years, and who didn’t have any contraindications to bronchoscopy procedures in H. Adam Malik General Hospital’s ICU underwent a BAL examination (culture and antibiotics resistance), then observed for 14 days to see the mortality.

Results:

Fourty-six patients' data were examined. Predominantly males (71,7%) and aged 41–60 years (45,6%), with Community-acquired Pneumonia (CAP) accounting for 39,1% of cases. By far the most common microorganism isolated was Acinetobacter baumannii (23,9%). According to BAL examinations of Pneumonia patients in the ICU, there is no relationship between microbial patterns or antibiotic resistance with mortality (p-value > 0.05).

Conclusions:

Microbiological patterns and antibiotic resistance are not the only factors influencing the mortality of patients with pneumonia in the ICU. Mortality can also be influenced by several variables, including comorbidities and the co-occurrence of other nosocomial infections, including bloodstream infections, surgical wounds, and urinary tract infections.